Simplex
AI agents to enroll providers with payors
Simplex is a business in b2b based in San Francisco, CA, USA, founded in 2015.
Profile
Simplex builds AI agents to handle provider enrollment end-to-end. We automate pulling provider data from CAQH, filling out enrollment forms + uploading licenses via payor portals/email/phone, updating applications when returned for corrections, and performing effective date follow-ups until a final determination is made, all autonomously.
The company sits in the b2b segment, where it competes on its core product or service.
San Francisco, CA, USA is where the company is located.
Its current recorded stage is Summer 2024.
The company reports a headcount in the 2 range.
Directory analysis
Simplex is a San Francisco‑based B2B startup founded in 2015 that builds AI agents to automate the entire provider enrollment process with payors. The agents pull provider data from CAQH, fill out enrollment forms, upload licenses via payor portals or other channels, update applications when corrections are requested, and track effective dates until a final determination is reached. With only two employees, the company focuses on end‑to‑end automation of administrative tasks in healthcare payer‑provider onboarding.
Positioning: Operating in the healthcare administrative technology sector, Simplex offers a niche, autonomous solution aimed at reducing manual effort in provider enrollment. Its small size and early‑stage status suggest a focused, specialized product rather than a broad enterprise platform.
Note: Simplex automates provider enrollment with AI agents.
Auto-generated directory analysis from public data · updated 12 Oct 2026. Informational only, not investment advice.
| Sector | B2B |
|---|---|
| Headquarters | San Francisco, CA, USA |
| Country | USA |
| Founded | 2015 |
| Employees | 2 |
| Stage | Summer 2024 |
Website: simplex.sh
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