MADORRA, INC.

At-home, ultrasonic device for treatment of vulvovaginal atrophy

MADORRA, INC. is a business in eunice kennedy shriver national institute of child health and human development based in PORTLAND, OR, founded in 2014.

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Abstract
Decreases in endogenous estrogen production during and after menopause or cancer treatment is associated
with decreased lubrication and thinning of the vaginal tissue, making it sensitive, friable, and inelastic.
Vulvovaginal Atrophy (VVA) leads to pain during sex, which contributes to lower libido, abstinence, strained
relationships, and often depression. VVA affects up to 90% of all peri- and postmenopausal women, which
represents up to 44.6M women in the US alone. By 2025, VVA is predicted to impact between 369-990M
postmenopausal women worldwide. VVA not only causes pain during sex, but it can also make it uncomfortable
to sit, stand, exercise, or urinate, significantly affecting quality of life whether women are sexually active or not.
Nearly 75% of breast cancer survivors (BCS)—1.4M women in the U.S.—receive adjuvant estrogen-suppressing
treatments to prevent cancer recurrence. These treatments exacerbate VVA, resulting in poor therapy
compliance and thereby placing these women at high risk for cancer recurrence. Hormone therapy (HT), the
most efficacious treatment for VVA, is associated with a higher risk of cancer, and therefore absolutely
contraindicated for BCS. Over-the-counter (OTC) lubricants and moisturizers are disdained by users as messy,
temporary, and simply not effective enough for the severity of symptoms endured. There is a critical need for an
aff

Within the eunice kennedy shriver national institute of child health and human development space, the company focuses on its core offering rather than a broad product line.

The business is associated with PORTLAND, OR.

Directory data places it at the SBIR/STTR stage.

The company reports a headcount in the 1-10 range.

Public records show total funding of about $486K.

Website: madorra.com