5H45

Functionalized Biomaterials Dedicated to Haircare

Operating in consumer bio based in France, 5H45 was founded in 2023.

Profile

5h45 is a biotechnology company reinventing how we style and care for hair. Founded by Lea Majerholc after a near-fatal reaction to a chemical straightening treatment, 5h45 was born to end the cycle of toxic, damaging products that dominate an $80 billion market. The company’s patented silk-based nanofilm forms a biomimetic layer around each hair fiber—shaping, repairing, and protecting it without harm. The result is smooth, frizz-free hair that resists humidity for months, yet remains fully reversible and biodegradable. Led by scientists from Tufts, Technion, and Prose, 5h45 unites biotechnology and beauty to deliver the first safe, high-performance alternative to keratin and relaxer treatments.

The company sits in the consumer bio segment, where it competes on its core product or service.

The business is associated with France.

Its current recorded stage is SOSV portfolio company.

Recorded headcount: 2-10 employees.

Website: 5h45.co